Yes. Angeles Crest Highway, AKA Hwy 2. We live near Wrightwood, ride it most weekends when weather permits. Newcombs Ranch is about halfway, (40miles) typically stop for a leg stretch and water break. Unfortunately they have not reopened after COVID... If you continue the whole length of ACH you come out in La Canada (Los Angeles). about 80 miles of canyons, 160 miles round trip. Great little stretch of road for day rides, and a quick way to cool down during the summer heat.
I’m thinking that’s the Angeles Crest Highway... northeast of Los Angeles, heading out through the San Gabriel Mountains. I haven’t been on it since the early 80s when I lived in LA, but the terrain & scenery does look like I recall.