Like koth442 I have owned and driven lots of big V2 bikes, and also inline 4, and never had any trouble with vibration/buzzing.
Before the Tracer goo GT I had the XSR 900 and that bike vibrated in such a way that my hands (most the right hand) fell asleep after driving for 30-45 minutes.
The vibration starts at around 4500-5000 rpm. Meaning highway/autobahn was the worst! I never had problems on other places, it was only autobahn that made my hands numb!
On the XSR 900 it was so bad that the mirrors became useless - couldn't see if the lights in the mirror was 1 or 8 cars! Looked like the mirrors were mounted on an electric sander...
The Trader goo GT is not so bad. It has cruise control and that lets me hold very light on the handle bar. Haven't had sleeping/numb hands on this bike yet, and I have just come back from a 4500km trip with 2000 of those km being on the autobahn. No problems with the vibrations.. But they can be felt in the foot pegs (I have FJR1300 rubberized footpegs) and handlebar. The mirrors are useful, but the right mirror is still a bit shakey. But both can be used!